Prkcg - protein kinase C, gamma

Predicted to enable calcium-dependent protein kinase C activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of cellular protein metabolic process; and response to morphine. Acts upstream of or within chemosensory behavior and regulation of phagocytosis. Located in several cellular components, including calyx of Held; postsynaptic density; and synaptic membrane. Is active in presynaptic cytosol. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 14. Orthologous to human PRKCG (protein kinase C gamma). [provided by Alliance of Genome Resources, Apr 2022]