Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Acts upstream of or within phosphatidylinositol biosynthetic process. Located in cytosol. Is expressed in several structures, including brain. Orthologous to human PIP5K1B (phosphatidylinositol-4-phosphate 5-kinase type 1 beta). [provided by Alliance of Genome Resources, Apr 2022]