Pim2 - proviral integration site 2

Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of autophagy; and protein stabilization. Acts upstream of or within several processes, including apoptotic mitochondrial changes; negative regulation of protein binding activity; and positive regulation of macroautophagy. Predicted to be active in cytoplasm. Is expressed in spleen and thymus. Orthologous to human PIM2 (Pim-2 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]