Mouse
Abcb4 - ATP-binding cassette, sub-family B (MDR/TAP), member 4
Alias:
Mdr2
Pgy2
Pgy-2
mdr-2
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Protein Interaction
Related Models
References
Predicted to enable ATPase-coupled intramembrane lipid transporter activity; ATPase-coupled transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in bile acid secretion and response to fenofibrate. Located in intercellular canaliculus and plasma membrane. Is expressed in alimentary system and liver. Used to study cholecystitis; cholestasis; hepatocellular carcinoma; intrahepatic cholestasis; and primary sclerosing cholangitis. Human ortholog(s) of this gene implicated in cholestasis (multiple); gallbladder disease; and liver cirrhosis (multiple). Orthologous to human ABCB4 (ATP binding cassette subfamily B member 4). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Models
Reference
5
28
65613 bp
140.38
5
18
Abcb4 Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Selected Gene:
Mouse:Abcb4
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Expression
Alphabetical
Cell-specific RNA expression
Organ
Expression
Alphabetical
Protein Interaction
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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