Enables fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in several processes, including fructose 2,6-bisphosphate metabolic process; monocarboxylic acid metabolic process; and positive regulation of glucokinase activity. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2). [provided by Alliance of Genome Resources, Apr 2022]