Pcsk2 - proprotein convertase subtilisin/kexin type 2

Enables serine-type endopeptidase activity. Involved in enkephalin processing and protein autoprocessing. Acts upstream of or within nervous system development and proteolysis. Located in extracellular space. Is expressed in brain; endocrine gland; future brain; and gut. Human ortholog(s) of this gene implicated in myocardial infarction and type 2 diabetes mellitus. Orthologous to human PCSK2 (proprotein convertase subtilisin/kexin type 2). [provided by Alliance of Genome Resources, Apr 2022]