Pcsk1 - proprotein convertase subtilisin/kexin type 1

Enables identical protein binding activity and serine-type endopeptidase activity. Involved in peptide biosynthetic process and peptide hormone processing. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; female reproductive system; and nose. Used to study obesity. Human ortholog(s) of this gene implicated in obesity and proprotein convertase 1/3 deficiency. Orthologous to human PCSK1 (proprotein convertase subtilisin/kexin type 1). [provided by Alliance of Genome Resources, Apr 2022]