Kat2b - K(lysine) acetyltransferase 2B

Enables several functions, including N-acetyltransferase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and transcription coactivator activity. Involved in internal peptidyl-lysine acetylation and negative regulation of cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within histone H3-K9 acetylation; positive regulation of gluconeogenesis; and positive regulation of transcription by RNA polymerase II. Located in several cellular components, including actomyosin; kinetochore; and sarcomere. Part of ATAC complex. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and lung. Orthologous to human KAT2B (lysine acetyltransferase 2B). [provided by Alliance of Genome Resources, Apr 2022]