Pax7 - paired box 7

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and positive regulation of nitrogen compound metabolic process. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; sensory organ; and skeletal musculature. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to human PAX7 (paired box 7). [provided by Alliance of Genome Resources, Apr 2022]