Nobox - NOBOX oogenesis homeobox

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within ovarian follicle development. Located in cytoplasm. Is expressed in several structures, including eye; genitourinary system; heart; liver; and musculoskeletal system. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Orthologous to human NOBOX (NOBOX oogenesis homeobox). [provided by Alliance of Genome Resources, Apr 2022]