Slc11a2 - solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Enables cobalt ion transmembrane transporter activity; ferrous iron transmembrane transporter activity; and proton transmembrane transporter activity. Acts upstream of or within several processes, including cation transport; erythrocyte development; and multicellular organismal iron ion homeostasis. Located in several cellular components, including brush border membrane; endosome; and extracellular vesicle. Is integral component of plasma membrane. Is expressed in embryo; intestine; small intestine; and yolk sac. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; anemia; and hypochromic anemia. Orthologous to human SLC11A2 (solute carrier family 11 member 2). [provided by Alliance of Genome Resources, Apr 2022]