Mouse
Slc11a1 - solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Alias:
Bcg
Ity
Lsh
ity
Ity1
Nramp
Nramp1
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables manganese ion transmembrane transporter activity. Involved in metal ion export. Acts upstream of or within several processes, including cation homeostasis; defense response to other organism; and positive regulation of macromolecule metabolic process. Located in cytoplasmic vesicle and lysosome. Is expressed in several structures, including brain; gut; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Buruli ulcer disease; autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to human SLC11A1 (solute carrier family 11 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
15
15657 bp
59.74
6
11
Slc11a1 Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Sources
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