Nqo1 - NAD(P)H dehydrogenase, quinone 1

Enables NAD(P)H dehydrogenase (quinone) activity. Acts upstream of or within negative regulation of catalytic activity and response to oxidative stress. Predicted to be located in cytoplasm; dendrite; and neuronal cell body. Predicted to be active in cytosol. Is expressed in heart; main olfactory bulb; olfactory epithelium; and skin. Human ortholog(s) of this gene implicated in several diseases, including asthma; hematologic cancer (multiple); lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]