Nme2 - NME/NM23 nucleoside diphosphate kinase 2

Predicted to enable several functions, including G-quadruplex DNA binding activity; anion binding activity; and kinase activity. Predicted to be involved in several processes, including negative regulation of myeloid leukocyte differentiation; nucleotide metabolic process; and protein autophosphorylation. Predicted to act upstream of or within nucleotide metabolic process and phosphorylation. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in teratoma. Orthologous to several human genes including NME1-NME2 (NME1-NME2 readthrough). [provided by Alliance of Genome Resources, Apr 2022]