Nfe2 - nuclear factor, erythroid derived 2

Predicted to enable several functions, including WW domain binding activity; identical protein binding activity; and protein N-terminus binding activity. Predicted to contribute to cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and negative regulation of syncytium formation by plasma membrane fusion. Located in nucleus. Is expressed in several structures, including dorsal aorta; eye; genitourinary system; limb; and yolk sac. Orthologous to human NFE2 (nuclear factor, erythroid 2). [provided by Alliance of Genome Resources, Apr 2022]