Nfatc2 - nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of gene expression. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; myotube cell development; and positive regulation of myoblast fusion. Located in chromatin; cytosol; and nucleus. Part of ribonucleoprotein complex and transcription regulator complex. Is expressed in several structures, including brain; genitourinary system; jaw; spinal cord; and thymus primordium. Orthologous to human NFATC2 (nuclear factor of activated T cells 2). [provided by Alliance of Genome Resources, Apr 2022]