Neurod2 - neurogenic differentiation 2

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and protein heterodimerization activity. Involved in several processes, including cellular response to electrical stimulus; regulation of synapse maturation; and regulation of transcription, DNA-templated. Acts upstream of or within associative learning; behavioral fear response; and neuron development. Located in nucleus. Is expressed in several structures, including genitourinary system; limb; and nervous system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 72. Orthologous to human NEUROD2 (neuronal differentiation 2). [provided by Alliance of Genome Resources, Apr 2022]