Neb - nebulin

Predicted to enable actin filament binding activity. Predicted to be involved in cardiac muscle thin filament assembly. Predicted to act upstream of or within regulation of actin filament length and sarcomere organization. Located in Z disc. Is expressed in trunk dermomyotome. Used to study nemaline myopathy 2. Human ortholog(s) of this gene implicated in nemaline myopathy 2. Orthologous to human NEB (nebulin). [provided by Alliance of Genome Resources, Apr 2022]