Predicted to be involved in positive regulation of cytochrome-c oxidase activity. Located in mitochondrial inner membrane. Part of mitochondrial respiratory chain complex I and mitochondrial respiratory chain complex IV. Is expressed in several structures, including alimentary system; central nervous system; integumental system; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human NDUFA4 (NDUFA4 mitochondrial complex associated). [provided by Alliance of Genome Resources, Apr 2022]