Naip5 - NLR family, apoptosis inhibitory protein 5
Alias:
Lgn1
Birc1e
Naip-rs3
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Basic Information
Sequence Homology
Transcripts & Proteins
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Enables ATP binding activity. Involved in several processes, including positive regulation of interleukin-1 beta production; pyroptosis; and response to bacterium. Acts upstream of or within entry of bacterium into host cell. Part of IPAF inflammasome complex. Is expressed in several structures, including central nervous system; genitourinary system; heart; liver; and retina. Orthologous to human NAIP (NLR family apoptosis inhibitory protein). [provided by Alliance of Genome Resources, Apr 2022]