Myt1l - myelin transcription factor 1-like

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II; neuron development; and neuron fate specification. Located in nucleus. Is expressed in several structures, including eye; genitourinary system; nervous system; and olfactory epithelium. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]