Mouse
Myo7a - myosin VIIA
Alias:
Hdb
sh1
Myo7
sh-1
USH1B
polka
nmf371
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables protein domain specific binding activity. Involved in cellular protein localization. Acts upstream of or within several processes, including animal organ morphogenesis; phagolysosome assembly; and pigment granule transport. Located in several cellular components, including melanosome; photoreceptor connecting cilium; and stereocilium base. Is active in stereocilium. Is expressed in central nervous system; liver; sensory organ; and small intestine epithelium. Used to study Usher syndrome type 1 and autosomal recessive nonsyndromic deafness 2. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Usher syndrome (multiple); auditory system disease (multiple); and congenital nystagmus. Orthologous to human MYO7A (myosin VIIA). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11
49
68470 bp
254.94
25
16
Myo7a Genetics information (-)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Sources
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