Acts upstream of or within actin-mediated cell contraction; plasma membrane repair; and response to activity. Located in several cellular components, including A band; Golgi apparatus; and actomyosin contractile ring. Is expressed in several structures, including alimentary system; forelimb bud mesenchyme; and skeletal musculature. Human ortholog(s) of this gene implicated in inclusion body myositis and proximal myopathy and ophthalmoplegia. Orthologous to human MYH2 (myosin heavy chain 2). [provided by Alliance of Genome Resources, Apr 2022]