Mtf1 - metal response element binding transcription factor 1

Enables DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone acetyltransferase binding activity. Involved in cellular response to zinc ion and transcription, DNA-templated. Acts upstream of or within positive regulation of transcription by RNA polymerase II; response to cadmium ion; and response to oxidative stress. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; cardiovascular system; early conceptus; genitourinary system; and gut. Orthologous to human MTF1 (metal regulatory transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]