Sik1 - salt inducible kinase 1

Enables several functions, including ATP binding activity; cAMP response element binding protein binding activity; and enzyme binding activity. Involved in several processes, including anoikis; entrainment of circadian clock by photoperiod; and regulation of cellular biosynthetic process. Acts upstream of or within regulation of cell differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 30. Orthologous to human SIK1 (salt inducible kinase 1). [provided by Alliance of Genome Resources, Apr 2022]