Mras - muscle and microspikes RAS

Predicted to enable GTP-dependent protein binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; branchial arch; dorsal root ganglion; future spinal cord; and limb bud. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Orthologous to human MRAS (muscle RAS oncogene homolog). [provided by Alliance of Genome Resources, Apr 2022]