Mpdz - multiple PDZ domain crumbs cell polarity complex component

Predicted to enable protein C-terminus binding activity. Involved in dendrite development and intracellular protein transport. Acts upstream of or within cell adhesion. Located in several cellular components, including Schmidt-Lanterman incisure; apical plasma membrane; and bicellular tight junction. Part of subapical complex. Is active in synapse. Is expressed in several structures, including central nervous system; early conceptus; olfactory epithelium; and retina. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human MPDZ (multiple PDZ domain crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Apr 2022]