Enables deacetylase activity and sulfotransferase activity. Acts upstream of or within heparan sulfate proteoglycan biosynthetic process; mast cell mediated immunity; and regulation of angiotensin levels in blood. Located in Golgi apparatus. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human NDST2 (N-deacetylase and N-sulfotransferase 2). [provided by Alliance of Genome Resources, Apr 2022]