Mertk - MER proto-oncogene tyrosine kinase

Predicted to enable transmembrane receptor protein tyrosine kinase activity. Acts upstream of or within several processes, including animal organ development; neutrophil clearance; and protein kinase B signaling. Predicted to be located in several cellular components, including extracellular space; photoreceptor outer segment; and rhabdomere. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; immune system; and retina. Human ortholog(s) of this gene implicated in retinitis pigmentosa 38. Orthologous to human MERTK (MER proto-oncogene, tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]