Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone deacetylase binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be part of transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart; and musculature. Orthologous to human MEF2B (myocyte enhancer factor 2B). [provided by Alliance of Genome Resources, Apr 2022]