Cd46 - CD46 antigen, complement regulatory protein

Predicted to enable cadherin binding activity. Predicted to contribute to endopeptidase activity. Predicted to be involved in several processes, including positive regulation of T cell activation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Predicted to act upstream of or within single fertilization. Predicted to be located in several cellular components, including Golgi apparatus; basolateral plasma membrane; and inner acrosomal membrane. Predicted to be active in plasma membrane. Is expressed in testis. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; hemolytic-uremic syndrome; meningococcal meningitis; multiple sclerosis; and pre-eclampsia. Orthologous to human CD46 (CD46 molecule). [provided by Alliance of Genome Resources, Apr 2022]