Max - Max protein

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; lens; limb cartilage condensation; and liver. Human ortholog(s) of this gene implicated in lung small cell carcinoma and pheochromocytoma. Orthologous to human MAX (MYC associated factor X). [provided by Alliance of Genome Resources, Apr 2022]