Mark3 - MAP/microtubule affinity regulating kinase 3

Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; peptidyl-serine autophosphorylation; and positive regulation of protein binding activity. Predicted to act upstream of or within phosphorylation. Predicted to be located in dendrite. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Human ortholog(s) of this gene implicated in visual impairment and progressive phthisis bulbi. Orthologous to human MARK3 (microtubule affinity regulating kinase 3). [provided by Alliance of Genome Resources, Apr 2022]