Dnah1 - dynein, axonemal, heavy chain 1

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in inner dynein arm assembly and sperm axoneme assembly. Predicted to act upstream of or within cilium movement involved in cell motility and epithelial cilium movement involved in extracellular fluid movement. Predicted to be located in axoneme and sperm flagellum. Predicted to be part of inner dynein arm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Orthologous to human DNAH1 (dynein axonemal heavy chain 1). [provided by Alliance of Genome Resources, Apr 2022]