Pde5a - phosphodiesterase 5A

Enables 3',5'-cyclic-GMP phosphodiesterase activity. Involved in several processes, including blood vessel diameter maintenance; response to testosterone; and short-term memory. Located in cytosol. Used to study artery disease (multiple); impotence (multiple); and primary biliary cholangitis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human PDE5A (phosphodiesterase 5A). [provided by Alliance of Genome Resources, Apr 2022]