Enables DNA N-glycosylase activity. Involved in response to oxidative stress. Located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]