Card14 - caspase recruitment domain family, member 14

Predicted to enable CARD domain binding activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of protein phosphorylation; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within apoptotic process. Predicted to be located in aggresome and cytosol. Predicted to be active in cytoplasm. Is expressed in gut; nose; and vibrissa. Used to study psoriasis 2. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Orthologous to human CARD14 (caspase recruitment domain family member 14). [provided by Alliance of Genome Resources, Apr 2022]