Prkcd - protein kinase C, delta

Enables TIR domain binding activity; calcium-independent protein kinase C activity; and protein kinase binding activity. Involved in several processes, including D-aspartate import across plasma membrane; positive regulation of MAP kinase activity; and positive regulation of glucose import. Located in several cellular components, including cytosol; mitochondrion; and nucleus. Is active in postsynaptic cytosol. Used to study brain ischemia and hypertension. Biomarker of hyperinsulinism; hypertension; muscular disease; obesity; and restrictive cardiomyopathy. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3 and fatty liver disease. Orthologous to human PRKCD (protein kinase C delta). [provided by Alliance of Genome Resources, Apr 2022]