Zbtb7a - zinc finger and BTB domain containing 7a

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone acetyltransferase binding activity. Involved in several processes, including hemopoiesis; nucleic acid metabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Part of DNA-dependent protein kinase complex. Colocalizes with site of double-strand break. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and retina. Orthologous to human ZBTB7A (zinc finger and BTB domain containing 7A). [provided by Alliance of Genome Resources, Apr 2022]