Anxa1 - annexin A1

Predicted to enable several functions, including calcium-dependent phospholipid binding activity; double-stranded DNA helicase activity; and phospholipase A2 inhibitor activity. Predicted to contribute to single-stranded RNA binding activity. Involved in several processes, including myoblast migration involved in skeletal muscle regeneration; neutrophil homeostasis; and positive regulation of neutrophil apoptotic process. Acts upstream of or within several processes, including arachidonic acid secretion; positive regulation of G1/S transition of mitotic cell cycle; and regulation of cell population proliferation. Located in several cellular components, including apical plasma membrane; lateral plasma membrane; and sarcolemma. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; skeleton; and skin. Human ortholog(s) of this gene implicated in brain ischemia and pancreatic cancer. Orthologous to human ANXA1 (annexin A1). [provided by Alliance of Genome Resources, Apr 2022]