Loricrin - loricrin cornified envelope precursor protein

A structural constituent of cytoskeleton and structural constituent of skin epidermis. Predicted to be involved in keratinocyte differentiation and peptide cross-linking. Predicted to act upstream of or within keratinization. Located in cornified envelope and cytoplasmic side of plasma membrane. Is expressed in several structures, including gut; male reproductive system; sensory organ; skin; and thymus. Orthologous to human LORICRIN (loricrin cornified envelope precursor protein). [provided by Alliance of Genome Resources, Apr 2022]