Lmo4 - LIM domain only 4

Predicted to enable metal ion binding activity. Involved in positive regulation of kinase activity and regulation of cell migration. Acts upstream of or within several processes, including cell differentiation in spinal cord; neural tube closure; and thymus development. Located in cell leading edge and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study anencephaly. Orthologous to human LMO4 (LIM domain only 4). [provided by Alliance of Genome Resources, Apr 2022]