Lhx5 - LIM homeobox protein 5

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription, DNA-templated and spinal cord association neuron differentiation. Acts upstream of or within brain development and cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation. Predicted to be active in nucleus. Is expressed in several structures, including future brain; limb; nervous system; sensory organ; and urinary system. Orthologous to human LHX5 (LIM homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]