Lama5 - laminin, alpha 5

Enables integrin binding activity. Acts upstream of or within several processes, including animal organ development; morphogenesis of an epithelium; and protein localization to plasma membrane. Located in basement membrane and neuromuscular junction. Part of laminin-10 complex. Is active in synaptic cleft. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; respiratory system; and sensory organ. Used to study cystic kidney disease. Orthologous to human LAMA5 (laminin subunit alpha 5). [provided by Alliance of Genome Resources, Apr 2022]