Ksr1 - kinase suppressor of ras 1

Enables several functions, including 14-3-3 protein binding activity; ATP binding activity; and Hsp90 protein binding activity. Involved in intracellular signal transduction; regulation of MAP kinase activity; and regulation of cell population proliferation. Acts upstream of or within positive regulation of MAPK cascade. Predicted to be located in cell projection and plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and lung. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to human KSR1 (kinase suppressor of ras 1). [provided by Alliance of Genome Resources, Apr 2022]