Krt8 - keratin 8

Predicted to enable scaffold protein binding activity. Acts upstream of or within several processes, including cell differentiation involved in embryonic placenta development; cell surface receptor signaling pathway; and hepatocyte apoptotic process. Located in several cellular components, including Z disc; apicolateral plasma membrane; and sarcolemma. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT8 (keratin 8). [provided by Alliance of Genome Resources, Apr 2022]