Krt10 - keratin 10

Enables cytoskeletal protein binding activity. Involved in positive regulation of epidermis development. Acts upstream of or within cellular response to calcium ion; intermediate filament organization; and keratinocyte development. Located in keratin filament. Is expressed in several structures, including alimentary system; lower urinary tract; respiratory system; sensory organ; and skin. Used to study epidermolytic hyperkeratosis. Human ortholog(s) of this gene implicated in epidermolytic hyperkeratosis. Orthologous to human KRT10 (keratin 10). [provided by Alliance of Genome Resources, Apr 2022]