Kpna1 - karyopherin (importin) alpha 1

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in postsynapse to nucleus signaling pathway. Acts upstream of or within several processes, including NLS-bearing protein import into nucleus; satellite cell activation involved in skeletal muscle regeneration; and skeletal muscle satellite cell proliferation. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; gut; integumental system; and sensory organ. Orthologous to human KPNA1 (karyopherin subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]