Kif5a - kinesin family member 5A

Enables kinesin binding activity and microtubule binding activity. Involved in anterograde dendritic transport of neurotransmitter receptor complex and vesicle-mediated transport. Located in several cellular components, including ciliary rootlet; neuron projection; and neuronal cell body. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; hereditary spastic paraplegia 10; multiple sclerosis; prostate cancer; and rheumatoid arthritis. Orthologous to human KIF5A (kinesin family member 5A). [provided by Alliance of Genome Resources, Apr 2022]