Kcnq1 - potassium voltage-gated channel, subfamily Q, member 1
Alias:
Kcna9
KVLQT1
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables voltage-gated potassium channel activity. Involved in several processes, including animal organ development; inorganic ion homeostasis; and regulation of heart contraction. Acts upstream of or within circulatory system development; negative regulation of gene expression; and regulation of gene expression by genetic imprinting. Located in apical part of cell; neuron projection; and transport vesicle. Part of voltage-gated potassium channel complex. Is active in several cellular components, including apical plasma membrane; basolateral part of cell; and ciliary base. Is expressed in several structures, including alimentary system; extraembryonic component; heart; hemolymphoid system gland; and reproductive system. Used to study Jervell-Lange Nielsen syndrome and long QT syndrome 1. Human ortholog(s) of this gene implicated in heart conduction disease (multiple) and long QT syndrome (multiple). Orthologous to human KCNQ1 (potassium voltage-gated channel subfamily Q member 1). [provided by Alliance of Genome Resources, Apr 2022]